AstraZeneca may have included ‘outdated information’ in Covid vaccine trial

today03/23/2021 20

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AstraZeneca may have included ‘outdated information’ in Covid vaccine trial

Via CNBC.com:

A U.S. health agency on Tuesday said that AstraZeneca may have included outdated information in trial results of its Covid-19 vaccine, potentially casting doubt over published efficacy rates.

It comes just one day after the findings of a large U.S. trial showed that the vaccine was safe and highly effective and throws into question whether AstraZeneca can seek U.S. clearance for the vaccine next month as planned.

The Data Safety Monitoring Board “expressed concern that AstraZeneca may have included outdated information from that trial, which may have provided an incomplete view of the efficacy data,” the U.S. National Institute of Allergy and Infectious Diseases said in a statement.

“We urge the company to work with the DSMB to review the efficacy data and ensure the most accurate, up-to-date efficacy data be made public as quickly as possible.”

The NIAID said it was notified of the concerns late Monday, along with AstraZeneca and the Biomedical Advanced Research and Development Authority. Led by White House Chief Medical Advisor Dr. Anthony Fauci, the NIAID is part of the National Institutes of Health.

On Monday, U.S. trial results showed that the coronavirus vaccine developed by AstraZeneca and the University of Oxford is 79% effective in preventing symptomatic illness and 100% effective against severe disease and hospitalization.

The findings were welcomed as “surprisingly positive” and “good news for the global community.” It was thought the trial data could help to bolster public confidence after a flurry of countries had temporarily suspended their use of the vaccine amid safety concerns.

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