World Health Organization Warns Of ‘False Positives’ In COVID Tests

World Health Organization Warns Of ‘False Positives’ In COVID Tests

Via Just The News:

The World Health Organization is warning that widely deployed technology used to test for COVID-19 may, if interpreted incorrectly, lead at least some patients to believe they have the virus when in fact they are not “truly infected.”

In a “medical product alert” issued last week, the WHO said that anyone “interpreting results for [COVID-19] specimens tested using [polymerase chain reaction] methodology” should be aware that “careful interpretation of weak positive results is needed.”

The WHO’s alert specifically addresses a controversial aspect of COVID-19 PCR tests: the “cycle threshold,” or the number of amplification cycles the test must undergo before detecting a COVID-19 specimen.

If a test must go through a high number of cycles before detecting the COVID virus, it potentially indicates that the original viral specimen was weak and the patient from whom it came may not be infectious or even “truly infected,” as the WHO put it in its announcement.

In its alert, the WHO said that the cycle threshold “is inversely proportional to the patient’s viral load.”

“[D]isease prevalence alters the predictive value of test results; as disease prevalence decreases, the risk of false positive increases,” the alert states. “This means that the probability that a person who has a positive result (SARS-CoV-2 detected) is truly infected with SARS-CoV-2 decreases as prevalence decreases, irrespective of the claimed specificity.”

The WHO’s media relations arm did not address a question from Just the News about the prevalence of individuals who are not “truly infected” despite positive COVID-19 PCR tests.

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